Calvin D Roskelley Selected Research

dihydromotuporamine C

1/2009	Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis.
2/2004	The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange.

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Calvin D Roskelley Research Topics

Disease

28	Neoplasms (Cancer) 01/2022 - 11/2002
10	Breast Neoplasms (Breast Cancer) 01/2016 - 07/2003
3	Carcinoma (Carcinomatosis) 01/2022 - 02/2008
3	Neoplasm Metastasis (Metastasis) 03/2015 - 02/2010
2	Leukemia 01/2022 - 07/2005
2	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 01/2015
2	Pneumonia (Pneumonitis) 12/2021 - 01/2020
2	Inflammation (Inflammations) 12/2021 - 01/2019
2	Retinoblastoma (Glioblastoma, Retinal) 01/2016 - 01/2015
2	Ovarian Epithelial Carcinoma 03/2012 - 02/2008
2	Ovarian Neoplasms (Ovarian Cancer) 09/2004 - 03/2003
1	Asthma (Bronchial Asthma) 12/2021
1	Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) 12/2021
1	Proteinuria 10/2020
1	Kidney Diseases (Kidney Disease) 10/2020
1	Nephrosis 10/2020
1	Nephrotic Syndrome (Syndrome, Nephrotic) 10/2020
1	Infections 02/2015
1	Adenocarcinoma 04/2013
1	Osteosarcoma (Osteogenic Sarcoma) 04/2013
1	Melanoma (Melanoma, Malignant) 06/2010
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 07/2005
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 07/2005
1	Myeloid Sarcoma (Chloroma) 07/2005
1	Carcinogenesis 02/2004

Drug/Important Bio-Agent (IBA)

10	podocalyxinIBA 01/2022 - 08/2004
4	Pharmaceutical PreparationsIBA 11/2020 - 01/2009
3	MucinsIBA 11/2020 - 03/2012
3	AntigensIBA 11/2020 - 11/2002
3	AntibodiesIBA 11/2020 - 03/2012
3	Peptides (Polypeptides)IBA 05/2010 - 09/2005
2	EpitopesIBA 01/2022 - 11/2020
2	Indicators and Reagents (Reagents)IBA 01/2022 - 01/2016
2	PlasticsIBA 01/2022 - 05/2005
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 12/2021 - 09/2004
2	Small Interfering RNA (siRNA)IBA 01/2016 - 03/2015
2	SialomucinsIBA 01/2016 - 03/2012
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 02/2007
2	AcidsIBA 01/2016 - 05/2010
2	Cadherins (E-Cadherin)IBA 05/2013 - 02/2008
2	Biological ProductsIBA 05/2013 - 03/2013
2	IntegrinsIBA 04/2013 - 03/2012
2	Fibronectins (Fibronectin)IBA 03/2012 - 03/2003
2	2,5-dichloro-4-bromophenol (B 2)IBA 02/2010 - 09/2005
2	dihydromotuporamine CIBA 01/2009 - 02/2004
2	strongylophorine-26IBA 05/2007 - 05/2005
1	monomethyl auristatin EIBA 01/2022
1	Immunoconjugates (Immunoconjugate)IBA 01/2022
1	Bleomycin (Blenoxane)FDA LinkGeneric 12/2021
1	CytokinesIBA 12/2021
1	capmatinibIBA 12/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 12/2021
1	Polysaccharides (Glycans)IBA 11/2020
1	EnzymesIBA 11/2020
1	Puromycin AminonucleosideIBA 10/2020
1	Biomarkers (Surrogate Marker)IBA 10/2020
1	Surface-Active Agents (Surfactants)IBA 01/2020
1	LipidsIBA 01/2020
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2020
1	CollagenIBA 01/2017
1	ezrinIBA 01/2016
1	RNA (Ribonucleic Acid)IBA 01/2016
1	Ribavirin (Virazole)FDA LinkGeneric 01/2016
1	LaminsIBA 01/2016
1	Retinaldehyde (Retinal)IBA 01/2016
1	Monoclonal AntibodiesIBA 03/2015
1	integrin-linked kinaseIBA 01/2015
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 01/2015
1	sarasinoside A1IBA 05/2013
1	TriterpenesIBA 05/2013
1	Cell Adhesion MoleculesIBA 05/2013
1	SaponinsIBA 05/2013
1	DiterpenesIBA 04/2013
1	Protein Isoforms (Isoforms)IBA 02/2012
1	Phosphotransferases (Kinase)IBA 02/2011
1	IGF Type 1 Receptor (IGF 1 Receptor)IBA 02/2011
1	Insulin ReceptorIBA 02/2011
1	matrigelIBA 02/2011
1	Phenobarbital (Luminal)FDA Link 02/2011
1	BMS 754807IBA 02/2011
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 02/2011
1	Insulin-Like PeptidesIBA 02/2011
1	BMS 536924IBA 02/2011
1	GTP Phosphohydrolases (GTPases)IBA 06/2010
1	Actins (F Actin)IBA 06/2010
1	neopetrosiamide AIBA 05/2010
1	Integrin beta1IBA 05/2010
1	Mitochondrial DNA (mtDNA)IBA 01/2009
1	beta CateninIBA 02/2008
1	sodium-hydrogen exchanger regulatory factorIBA 02/2007
1	SodiumIBA 02/2004
1	Protons (Proton)IBA 02/2004
1	AlkaloidsIBA 02/2004
1	Proto-Oncogene Proteins p21(ras)IBA 02/2004
1	Estrogen Receptor alphaIBA 07/2003

Therapy/Procedure

5	Therapeutics 01/2022 - 01/2015
2	Immunotherapy 11/2020 - 03/2015
1	Drug Therapy (Chemotherapy) 01/2015